Separation of Biomass Fermentation Products

Separation of Biomass Fermentation Products

During the biomass conversion process, the separation of fermentation products plays a crucial role. Following pretreatment, enzymatic hydrolysis, and fermentation, biomass contains a complex composition of cellulose, hemicellulose, lignin, as well as energy substances like methanol and ethanol, and lignin monomers and oligomers. Consequently, there arises the challenge of efficiently recycling materials while maintaining a high recovery rate. CD BioSicences offers comprehensive solutions to assist customers in establishing and attaining high-yield recovery of target products, ensuring optimal resource utilization.

Fermentation Products SeparationFig 1. Main steps for obtaining pure 1,3-PD (broth fermentation, biomass separation, flocculation, concentration, purification) (Laura M, et al., 2020)

Overview of Biomass Fermentation Products Separation

Biomass fermentation is a widely utilized process for the production of valuable biofuels and biochemicals. However, the separation of these products from the fermentation broth presents a significant challenge due to their dilute nature and complex composition. CD BioSicences, as a prominent industry player, aims to advance this field and provide innovative solutions for the separation of biomass fermentation products.

  • Gas Stripping: An Effective Approach

Gas stripping has emerged as a simple yet effective method for removing product inhibition in biomass fermentation. It involves using a carrier gas, such as fermentation off-gas (CO2 and H2) or an inert gas, to extract the desired products from the fermentation broth.

  • Liquid-Liquid Extraction: Separating Valuable Components

Liquid-liquid extraction is another promising technique for separating biomass fermentation products. This method exploits the differences in solubility and partitioning of the target products between two immiscible liquid phases. Various extraction solvents, such as oleyl alcohol, n-dodecanol, and butyl acetate, have been investigated for the extraction of ethanol and butanol from aqueous solutions.

  • Membrane Technologies: Pervaporation and Beyond

Membrane technologies, including pervaporation, hold great potential for the separation and purification of biomass fermentation products. Pervaporation employs a selective membrane to preferentially transport one component over another based on permeability differences.

  • Adsorption: Capturing Valuable Molecules

Adsorption is a widely employed method for the separation and purification of biomass fermentation products. It relies on the preferential adsorption of desired molecules onto a solid adsorbent material. This technique has been successfully applied to separate butanol from fermentation broths.

  • Integrated Fermentation-Separation Processes: Maximizing Efficiency

To enhance substrate utilization and overall productivity in biomass fermentation, researchers have explored integrated fermentation-separation processes. These processes aim to simultaneously remove desired products from the fermentation broth, reducing product inhibition and improving fermentation performance. Gas stripping, liquid-liquid extraction, membrane technologies, and adsorption can be integrated into the fermentation system, enabling in situ product recovery and concentration. By combining these techniques, overall production costs can be reduced, making biomass fermentation a more economically viable option.

Our Services

  • Membrane Filtration Services

Our Membrane Filtration Services offer cutting-edge solutions for the efficient separation and purification of biomass fermentation products. Utilizing advanced membrane technologies, we enable precise filtration at micro, ultra, and nano levels, ensuring high-quality output and minimal loss of valuable components.

  • Adsorption and Ion Exchange

Maximize the purity and yield of your biomass fermentation products with our sophisticated Adsorption and Ion Exchange services. Our state-of-the-art adsorption materials and ion exchange resins are designed to selectively remove impurities and enhance product concentration, providing a highly refined end product.

  • Distillation and Evaporation

Achieve superior separation with our Distillation and Evaporation services. Our systems are tailored to efficiently handle the complex mixtures typical of biomass fermentation processes, allowing for the effective separation of volatile and non-volatile components. We ensure optimized energy usage and high purity of distilled products.

  • Solid-Liquid Separation

Our Solid-Liquid Separation solutions are engineered to seamlessly handle the diverse range of biomass fermentation by-products. Utilizing techniques such as centrifugation, filtration, and sedimentation, we ensure the effective segregation of solid particles from liquid phases, facilitating further processing and purification steps.

  • Bioreactor Design and Optimization

Enhance biomass fermentation efficiency with our Bioreactor Design and Optimization services. We provide custom-designed bioreactors that align with your specific process requirements, ensuring optimal microbial growth and product yield. Our expertise ensures enhanced bioprocess control and scalability.

  • Process Integration and Automation

Streamline your biomass fermentation operations with our Process Integration and Automation services. By incorporating advanced automated systems and integrating various process stages, we facilitate seamless, continuous, and highly efficient production workflows, reducing manual intervention and operational costs.

  • Waste Management and Recycling

Our Waste Management and Recycling services are dedicated to promoting sustainable practices within the biomass fermentation industry. We provide comprehensive solutions for the treatment and recycling of fermentation waste, enabling resource recovery and minimizing environmental impact. Embrace eco-friendly processes with our expert waste management strategies.

Our Advantages

At CD BioSicences, we take pride in offering top-notch biomass fermentation products separation services to biology experts and industry professionals. With our expertise and commitment to excellence, we aim to provide customized solutions tailored to meet the unique needs of our clients.

  • One-stop separation service

We offer a comprehensive range of services, from laboratory scale to pilot scale and large scale.

  • Efficient upstream and downstream process development

Our team of experts excels in developing efficient processes for both upstream and downstream operations.

How to Place an Order

How to Place an Order

CD BioSicences is your trusted partner, contact us today to discuss your specific requirements and let us provide you with tailored solutions that meet your needs with utmost efficiency and reliability.

References

  1. Laura M,  Loredana FL, et al. "Separation and Purification of Biogenic 1,3-Propanediol from Fermented Glycerol through Flocculation and Strong Acidic Ion-Exchange Resin" Biomolecules 2020, 10(12):1601.
  2. Olawumi OS, Olayile E, et al. "Membrane Purification Techniques for Recovery of Succinic Acid Obtained from Fermentation Broth during Bioconversion of Lignocellulosic Biomass: Current Advances and Future Perspectives" Sustainability  2021, 13(2):6794.

Our products and services are for research use only and cannot be used for any clinical purposes.

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