CD BioSciences is a leading bioenvironmental company dedicated to providing cutting-edge solutions for species identification and environmental monitoring. Our expertise lies in harnessing the power of protein microarrays, a revolutionary technology that offers unparalleled accuracy, sensitivity, and efficiency in identifying a wide range of organisms.
Fig 1. Developments and Applications of Protein Microarrays (Luis B.,
et al., 2010)
Introduction to Protein Microarray Services
Protein microarray services provide a comprehensive platform for identifying and characterizing biological species across diverse ecosystems. By leveraging the unique protein profiles of different organisms, we offer precise and reliable identification solutions for various applications, from pathogen detection and environmental monitoring to food safety and biodefense.
Technical Principles
Protein microarrays are miniaturized platforms containing thousands of microscopic spots, each harboring a specific capture molecule such as an antibody or protein. When a sample containing unknown proteins is introduced to the array, target proteins bind to their corresponding capture molecules, generating a distinct binding pattern. This pattern serves as a unique fingerprint for species identification.
Technical Features
- High Throughput: Analyze thousands of proteins simultaneously, enabling rapid and efficient species identification.
- Exceptional Sensitivity: Detect even trace amounts of target proteins, facilitating the identification of species in complex samples.
- Unmatched Specificity: Differentiate between closely related species with high accuracy.
- Versatility: Adaptable to identify a broad spectrum of organisms, including bacteria, viruses, fungi, plants, and animals.
Technical Classification
- Antibody Microarrays: Utilize antibodies as capture molecules to detect specific proteins or antigens associated with different species.
- Functional Protein Microarrays: Employ proteins with specific functions to identify and characterize the functional properties of unknown proteins in a sample.
- Reverse-Phase Protein Microarrays: Analyze the expression levels of specific proteins in a sample, providing insights into cellular processes and disease states.
Application Filds
Protein microarray services cater to a diverse range of applications:
- Pathogen Detection and Surveillance: Rapidly identify and characterize disease-causing microorganisms in clinical, environmental, and food samples, aiding in disease surveillance and outbreak prevention.
- Environmental Monitoring and Biodiversity Assessment: Monitor the presence and abundance of specific species in various ecosystems, facilitating biodiversity assessments and conservation efforts.
- Food Safety and Authenticity Testing: Detect contaminants, allergens, and adulterants in food products, ensuring food safety and authenticity.
- Biodefense and Security: Identify potential biothreat agents and monitor for the presence of biological weapons.
- Agricultural and Veterinary Diagnostics: Detect plant pathogens and animal diseases, aiding in disease control and prevention.
Environmental Benefits
Protein microarray services contribute significantly to environmental sustainability by:
- Reducing reliance on traditional, time-consuming, and resource-intensive identification methods.
- Enabling rapid detection and monitoring of invasive species, facilitating timely intervention and mitigating ecological damage.
- Supporting the development of targeted bioremediation strategies by identifying key microbial players involved in pollutant degradation.
- Facilitating the assessment of environmental health and the impact of pollution on biodiversity.
Our Services
we pride ourselves on offering cutting-edge protein microarrays services that empower researchers and clinicians to explore the proteome with unprecedented precision and efficiency. Our services are designed to cater to a wide range of applications, from basic research to clinical diagnostics, and we are committed to delivering the highest quality data and support to our clients:
- Analytical Protein Microarrays: We provide analytical microarrays, predominantly antibody arrays, that focus on the detection of specific proteins. These arrays can detect targeted proteins through direct labeling or using a reporter antibody in a sandwich assay format, allowing for the multiplexed detection of antibodies to tumor antigens, as demonstrated in breast cancer research.
- Functional Protein Microarrays: Our functional microarrays are ideal for studying protein interactions, including protein binding and enzyme-substrate reactions. They have been widely used in applications such as the identification of surface antigens on leukemias using an antibody microarray and the study of post-translational modifications.
- Reverse-Phase Protein Microarrays: We also offer reverse-phase protein microarrays, which involve immobilizing many different lysate samples on the same chip. This format is particularly useful for serum profiling and the discovery of potential autoantigen biomarkers.
- Protein-Protein Interaction Detection: Utilizing our Protoarray™ Microarray, you can detect novel protein-protein interactions, validate previously observed interactions, and confirm positive interactions using the identified interacting protein on the array as a probe in reciprocal experiments.
- Kinase Substrate Identification (KSI): Our services include the use of the Protoarray™ Human Protein Microarray v5.1 for KSI experiments, which aids in determining which signals are specific to your kinase of interest.
- Custom Microarray Services: We understand that every research project is unique, and we offer customized microarray services to meet specific experimental requirements.
Distinctive Service Features
- High-Throughput Technology: Our open platform technology allows for the screening of thousands of individual proteins in a single experiment, generating a wealth of information quickly and efficiently.
- Versatility: Our protein array technology can address protein interactions with a variety of molecules, including proteins, lipids, sugars, DNA, RNA, antibodies, and small molecules.
- Quality Assurance: We ensure reproducibility and an acceptable signal-to-noise ratio by recommending single-use for each protein microarray and providing detailed guidelines for storage and handling.
- Comprehensive Data Analysis: We offer analyzer software designed to analyze data and identify potential protein binding partners with a low false positive rate, saving time and effort.
Contact Us
By leveraging our advanced Protein Microarrays services, you can accelerate your research and increase the likelihood of discovering new biomarkers and understanding complex biological processes. Contact us today to learn more about how our services can support your scientific endeavors.
How to Place an Order
Reference
- Luis B., Angie E., et al "Protein Microarrays: Novel Developments and Applications" Pharmaceutical Research 2010, 28:1480-1499.
Our products and services are for research use only and cannot be used for any clinical purposes.
Protein Microarrays
