Mass Spectrometry

Introduction to Mass Spectrometry for Species Identification

Mass spectrometry is a powerful analytical technique that measures the mass-to-charge ratio of ions. In the context of biological species identification, this involves analyzing the unique protein and peptide profiles of organisms. Each species possesses a distinct proteome, a "fingerprint" of proteins, which can be accurately identified through mass spectrometry. This method offers significant advantages over traditional identification methods, such as morphological observation or DNA sequencing, particularly for complex samples, degraded material, or when rapid identification is crucial.

• MALDI-TOF MS: This technique is widely used for rapid and accurate identification of microorganisms, particularly bacteria and fungi. It is highly suitable for applications in clinical diagnostics, food safety, and environmental monitoring.
• LC-MS/MS: Liquid Chromatography coupled with tandem mass spectrometry (LC-MS/MS) is a powerful technique for analyzing complex protein mixtures. It offers high sensitivity and resolution, enabling the identification of a wider range of species and the study of protein modifications.
• Proteomics: We provide comprehensive proteomic analysis services, which involve the identification and quantification of the entire protein complement of a sample. This approach is valuable for understanding biological processes, identifying biomarkers, and studying the impact of environmental factors on organisms.

• Microbial Diversity Studies: Analyzing microbial communities in various environments, such as soil, water, and air, to understand their roles in ecosystem functioning and identify potential pathogens.
• Biomonitoring and Ecological Assessment: Assessing the impact of pollution, climate change, and other environmental stressors on biodiversity by analyzing the species composition and protein profiles of indicator organisms.
• Conservation Biology: Identifying endangered or invasive species, tracking wildlife populations, and monitoring the effectiveness of conservation efforts.
• Bioremediation: Monitoring the effectiveness of bioremediation strategies by identifying the microorganisms involved in the degradation of pollutants.
• Environmental Forensics: Tracing the source of pollution or identifying the origin of biological materials in environmental samples..

• By providing accurate and timely species identification and environmental monitoring data, our mass spectrometry services contribute to:
• Informed Conservation Efforts: Enabling evidence-based decision-making for the protection and management of endangered species and ecosystems.
• Effective Pollution Control: Facilitating the identification of pollution sources and the assessment of remediation strategies.
• Sustainable Resource Management: Supporting the sustainable use of natural resources by monitoring biodiversity and ecosystem health.

• Metabolomics Analysis: Utilizing high-resolution mass spectrometry, we can identify and quantify small molecules in biological samples, providing insights into metabolic pathways and the overall metabolic profile of organisms.
• Microbial Identification: Our MALDI-TOF MS technology is adept at classifying and identifying bacteria through protein profiling, offering a rapid and efficient method for microbial identification.
• Protein Analysis and Proteomics: We specialize in the analysis of proteins and protein complexes, including post-translational modifications, to support research in molecular and cellular biology.
• Environmental Contaminant Analysis: Our services extend to the detection and quantification of contaminants in environmental samples, contribute to ecotoxicology research and environmental monitoring.
• Food Safety and Toxicology: We provide mass spectrometry databases for the testing of pesticides, contaminants, veterinary drugs, mycotoxins, and perfluorinated chemicals (PFCs), ensuring the safety and quality of food products.
• Clinical Research and Forensic Toxicology: Our toxicology spectral library contains over 900 compounds of interest for testing prescription drugs, drugs of abuse, and toxins, supporting clinical research and forensic analyses.