Glucosamine-2-epimerase for Synthesis of Sialic Acid Substances 
Catalog Number IE-1382
Physical Form Liquid
Color Brown to dark brown
Dosage Parameters 0.1-1 kg/T of raw material
Source Microorganism
| Summary | The enzyme catalyzes the interconversion between N-acyl-D-glucosamine and N-acyl-D-mannosamine and is a key enzyme in the synthesis of N-acetyl-D-neuraminic acid, which is a precursor for the synthesis of other sialic acid substances. |
| Description | Glucosamine-2-epimerase is produced by submerged fermentation followed by separation, ultrafiltration and formulation. The enzyme catalyzes the interconversion between N-acyl-D-glucosamine and N-acyl-D-mannosamine and is a key enzyme in the synthesis of N-acetyl-D-neuraminic acid, which is a precursor for the synthesis of other sialic acid substances. |
| Mechanism | In the enzymatic synthesis of N-acetylneuraminic acid, the first step is the isomerization of N-acetyl-D-glucosamine to N-acetyl-D-mannosamine by N-acetylglucosamine-2-epimerase. Subsequently, N-acetyl-D-mannosamine condenses with pyruvic acid under the action of N-acetylneuraminate lyase to form N-acetylneuraminic acid. |
| Advantages | For the synthesis of sialic acid substances; interconversion between N-acyl-D-glucosamine and N-acyl-D-mannosamine. |
| Application | For the synthesis of N-acetyl-D-neuraminic acid, a precursor for other sialic acid substances. |
| Application Area |
Food Biosynthesis |
| Application Recommendation | The recommended dosage is 0.1-1 kg/T of raw material. The dosage has to be optimized based on real situation, the raw material specifications, product expectations and processing parameters. It is better to begin the test with the smallest quantity. |
| Dosage Parameters | 0.1-1 kg/T of raw material |
| Optimum Temp | 20-30°C |
| Effective Temp | 10-50°C |
| Optimal pH | 6.0-7.0 |
| Effective pH | 5.0-8.0 |
| Source | Microorganism |
| Physical Form | Liquid |
| Color | Brown to dark brown |
| Scope of Shipment | Worldwide |
| Package | 25 kg/jerry can (customizable) |
| Storage | Keep sealed in a dry place at below -8°C and avoid direct sunlight. |
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